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ZO skin products


Skincare Protocols | 

ZO® Product Layering

By ZO® Skin Health


A skincare regimen is made up of multiple products. For skincare newbies, it can be daunting to simply figure out which products are best suited for their skin’s needs, much less knowing the order in which they need to be applied.


The order of application for your skincare products is just as important as the products themselves.


ZO® Skin Health provides comprehensive solutions for creating and maintaining healthy skin for anyone regardless of age, ethnicity, unique skin condition or skin type. A ZO® regimen is built around the research + findings of Dr. Zein Obagi’s approach to skin health restoration. Our 3-step approach offers guidance on when to apply certain products.


Getting Skin Ready® is the first essential step to any regimen, consisting of the following:

Cleanse ­— wash away impurities, makeup and other debris on the surface of the skin.

Exfoliate — slough off dead skin cells to reveal instantly smoother skin. Exfoliation can also help improve product penetration, to enable more corrective products, such as serums and retinols, to work optimally.

Tone — minimize surface oils and clarify pores.


After Getting Skin Ready®, the skin is prepped to receive the next steps of a regimen. Prevent + Correct is a broad category that consists of solutions that help address skin concerns, such environmental damage, lines + wrinkles, skin discoloration and the appearance of redness. This step typically consists of 2-3 products but can vary depending on your skin’s needs and from the input from your skin health professional.

Next-generation Daily Power Defense and new Illuminating AOX Serum and are recommended to follow the Getting Skin Ready® step. They are comprehensively formulated with ZO’s exclusive technologies to provide advanced environmental protection + defend against premature signs of aging, which can benefit every regimen. Illuminating AOX Serum is indicated for AM use and Daily Power Defense for AM/PM.


What follows is determined by what your skin needs, and the order and specific products should be determined by your skin health professional.

It’s important to note that ZO® has four high-molecular weight products with slower absorption times: 10% Vitamin C Self-ActivatingGrowth Factor Serum Radical Night Repair and Pigment Control + Brightening Crème.  These products should be applied last for optimal product benefits to be achieved.

Prior to sunscreen, any Supplementary product can be applied. Eye, Hydrating + Calming and Body products can enhance the results of any regimen.


Protect is the final step that should never be overlooked. ZO’s Triple-Spectrum Protection® sunscreen products help shield the skin from the damaging effects of  not only UVA and UVB rays but blue light and infrared-A rays as well.

Looking to build or enhance a ZO® Regimen of your own? Check out of Regimen Finder quiz, which offers you a unique regimen recommendation based on a few questions about your skin’s needs + goals.

For more information on product layering for your specific ZO® regimen, speak to your ZO® skin health professional.


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