Ingredients | January 29 2025

How to layer niacinamide with other skincare ingredients

Niacinamide has become a favorite among skincare enthusiasts due to its versatility and benefits. Whether you're dealing with blemish, discoloration, fine lines, or dehydration, niacinamide can address these concerns without irritating your skin. 

To get the most out of this ingredient, though, it's important to know how to layer it with other skincare actives. In this guide, we'll explore when to use niacinamide and how to introduce it into your routine to maximize its effectiveness.

What is niacinamide?

Niacinamide is a water-soluble form of vitamin B3; an essential nutrient for maintaining healthy skin. It plays a key role in supporting your skin's barrier function, which helps retain moisture, protect against environmental stressors, and prevent inflammation. 

Niacinamide is gentle on skin while offering many benefits. It is suitable for all skin types and its multifunctionality allows it to address uneven skin tone, dullness, and oil production.

Benefits and compatibility

Niacinamide is a multi-tasking ingredient that works well with most other skincare actives. It can be used in conjunction with hydrating, exfoliating, and anti-aging products without causing reactions or diminishing effectiveness. Some key benefits include:

• Strengthens skin barrier: Niacinamide helps boost the production of ceramides. These are natural lipids in the skin that help lock in moisture and protect against pollutants and irritants. 
• Balances oil production: Sebum production is regulated, making it ideal for those with oily or blemish-prone skin. It helps keep pores clear and reduces the risk of breakouts.
• Reduces inflammation: Its anti-inflammatory properties make it great for calming redness and irritation, especially for those with sensitive or reactive skin. 
• Brightens and evens skin tone: Niacinamide can reduce discoloration and brighten dull skin, giving your complexion a more even, radiant look.
• Minimizes appearance of pores: By improving skin texture, niacinamide can make pores appear smaller and less noticeable. 

It acts as an excellent base ingredient that enhances the efficacy of other skincare products. When choosing what to pair with niacinamide, it's important to know what works well when trying to target specific skin concerns.

Layering niacinamide with hydrating ingredients

Hydration is a key component for healthy skin and niacinamide pairs well with hydrating ingredients. These combinations are particularly beneficial for people with dehydrated skin:

• Niacinamide + Hyaluronic Acid: Hyaluronic acid is a humectant that draws moisture into the skin, while niacinamide helps strengthen the skin's barrier to lock in moisture. When layering these ingredients, apply hyaluronic acid first on damp skin. Apply niacinamide to seal hydration. 
• Niacinamide + Glycerin: Glycerin preserves hydration levels while niacinamide strengthens the skin's barrier. Apply glycerin-based products first, followed by niacinamide.
• Niacinamide + Ceramides: Ceramides are the building blocks of a strong skin barrier. When layered with niacinamide, you create a powerful moisture-repair duo. Apply a ceramide-rich hydrator after niacinamide to reinforce the skin's barrier.

Using with exfoliants

Exfoliating ingredients like alpha hydroxy acids (AHAs), beta hydroxy acids (BHAs), and retinoids are used to remove dead skin cells, revealing a brighter, smoother complexion. However, they can sometimes cause irritation or dryness, especially if used too frequently. 

• Niacinamide + AHAs/BHAs: Chemical exfoliants like glycolic acid, lactic acid, and salicylic acid work to exfoliate the surface of the skin and clear pores. Niacinamide helps calm and balance the skin post-exfoliation, minimizing the potential for redness or sensitivity. Apply niacinamide after your exfoliant to replenish and repair.
• Niacinamide + Retinoids: Retinoids are powerful anti-aging ingredients that increase cell turnover and stimulate collagen production, but they can also cause irritation and dryness for those with dry or sensitive skin. Pairing niacinamide with retinol can help mitigate these side effects. Apply niacinamide in the morning and retinoids at night.

Pairing with anti-aging ingredients

Niacinamide works well alongside anti-aging ingredients, offering both preventative and restorative benefits. 

• Niacinamide + Peptides: Peptides are short chains of amino acids that help boost collagen production to promote firmer and smoother skin and reduce the appearance of wrinkles. Peptides are typically found in lighter serums so apply them first. 

Can you use niacinamide with vitamin C?

Niacinamide can be layered with antioxidants like vitamin C to create a powerful combination for brightening skin and fighting free radical damage. If you have sensitive skin, it's often recommended to use vitamin C in the morning and niacinamide at night. Alternatively, you can use both ingredients in the same routine if your skin tolerates it.

Introducing niacinamide into your routine

If you're new to the ingredient, start by introducing it slowly into your routine. While niacinamide is well-tolerated by most skin types, it's always good practice to patch test before applying it all over your face. 

Begin by using it once a day, preferably in the morning, as it helps protect the skin against environmental stressors. Gradually increase usage to twice daily if needed. 

Here's a simple routine to follow when layering niacinamide: 

• Cleanser: Start with a gentle, non-stripping cleanser.
• Toner: Follow up with a toner to balance and prep your skin.
• Serums: Apply hydrating serums like hyaluronic acid first, followed by niacinamide. Our technologically advanced skin brightener – Brightalive® – is clinically shown to visibly improve skin clarity and promote a brighter, more even complexion. 
• Moisturizer: Use a ceramide-rich hydrator to lock in moisture and strengthen your skin barrier.
• Sunscreen: Always finish with sunscreen during the day to protect your skin from UV damage.

Find your skincare regimen with ZO

Incorporating niacinamide into your routine is an easy way to achieve smoother, more resilient skin. Learn more about layering it correctly with other ingredients by contacting our team of Skin Health Specialists. Commit to your skin with ZO today.