Water (Aqua/Eau), Dimethicone, Butylene Glycol, Glycerin, Caprylyl Methicone, Dimethicone/PEG-10/15 Crosspolymer, PEG-12 Dimethicone/PPG-20 Crosspolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, Sodium Chloride, Caprylic/Capric Triglyceride, Lactobacillus Ferment, Scutellaria Baicalensis Root Extract, Pentylene Glycol, Hydrolyzed Sericin, Phospholipids, Sodium Citrate, Buddleja Davidii Meristem Cell Culture, Cordyceps Militaris Mycelium Extract, Glycyrrhiza Uralensis (Licorice) Root Extract, Melilotus Officinalis Extract, Diglucosyl Gallic Acid, Dipropylene Glycol, Xanthan Gum, Phenoxyethanol, Pichia Ferment Lysate Filtrate, Caprylyl Glycol, Lavandula Stoechas Extract, Hexylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Tocopherol, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Phenylpropanol, Palmitoyl Dipeptide-61 D-Leucine Dipeptide-62 D-Alanine Dipeptide-63 Amide, Polyvinyl Alcohol, Caprooyl Tetrapeptide-3, Dextran, Palmitoyl Tripeptide-95 Norleucyl Dipeptide-72 D-Phenylalanine sh-Hexapeptide-15 SP Amide, Arginine/Lysine Polypeptide.
Neck Complex Anti-Aging + Brightening Serum is a high-potency product. It is only available for purchase via our network of clinical professionals.
Find a ProfessionalGive your neck the care your face gets. This dual-action serum is made for the neck and décolleté, visibly smoothing crepey skin and deep horizontal lines, firming for a more lifted looking and visibly defined contour, and brightening uneven tone. Clinically shown renewal for smoother, more even skin.
Clinically tested | Free of Paraben, SLS, SLES, Phthalates, and Gluten
All skin types
Neck lines and contour
Firming and lift
Brightness and even tone
Wrinkles and crepey skin
ZPRO®: Antioxidant and biomimetic protein complex supports skin’s natural replenishment of collagen + hyaluronic acid.
Pichia Ferment Lysate: A biopeptide that enhances skin’s natural radiance + hydration for a smoother appearance, while also improving the look of skin thickness for a more supple, youthful looking complexion.
Arginine/Lysine Polypeptide: Advanced plant-derived active provides firming + lifting benefits for a visibly more lifted neck contour. Enhances skin’s elasticity and reduces the appearance of deeper horizontal wrinkles in the neck.
Diglucosyl Gallic Acid: Targets 7 key factors that contribute to uneven skin tone resulting in a visibly more even, uniform complexion.
Intelligent peptide drone: Precision-driven encapsulated peptide aids in fast onset of skin brightening
Mentioned in February’s Best Beauty Launches 2026 - Beauty News Daily
CLINICALLY SHOWN RESULTS
Visible Neck Renewal in Just 12 Weeks*
EXPERT GUIDANCE
Use after cleansing, exfoliating, and toning skin, AM and PM.
Apply to the neck and décolleté in gentle, upward and outward motions to support lymphatic drainage and avoid mechanical stress that could exacerbate skin laxity.
Visible renewal of the neck & décolleté
TRUSTED BY PROFESSIONALS
"The neck requires intention, not leftovers. Neck Complex Anti-Aging+Brightening Serum is part of my daily routine because it visibly firms, smooths texture, and restores brightness where aging shows first."
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Frequently Asked Questions
What does ZO Neck Complex do?
ZO® Neck Complex Anti-Aging + Brightening Serum is a multi-faceted serum formulated specifically for the neck and décolleté. Clinically shown to firm and tighten the appearance of skin for a visibly more defined neck contour, it also delivers a more even-looking skin tone and reduces the appearance of crepey skin, lines and wrinkles, including deeper horizontal neck lines. It is backed by a 12-week independent, third-party clinical study of 46 subjects (females, ages 37-64, Fitzpatrick skin types I-VI).
How do I use ZO Neck Complex?
After Getting Skin Ready®, apply ZO® Neck Complex Anti-Aging + Brightening Serum to the neck and décolleté morning and evening. In the morning, follow with a broad-spectrum SPF 40 or higher sunscreen. Use as directed by your physician.
Is ZO Neck Complex the same as a neck cream?
Yes. ZO® Neck Complex Anti-Aging + Brightening Serum is often searched for as a "neck cream." It is a targeted serum designed specifically for the thinner, more delicate skin of the neck and décolleté area, where signs of aging present differently than on the face.
What size does ZO Neck Complex come in?
ZO® Neck Complex Anti-Aging + Brightening Serum is available in one size: 50 mL / 1.7 Fl. Oz.
What key ingredients are in ZO Neck Complex?
ZO® Neck Complex Anti-Aging + Brightening Serum is powered by five key actives: ZPRO® (antioxidant and biomimetic protein complex for collagen and hyaluronic acid support); Pichia Ferment Lysate (biopeptide for radiance, hydration, and skin thickness); Arginine/Lysine Polypeptide (plant-derived active for neck firming, lifting, and visible reduction of horizontal wrinkles); Diglucosyl Gallic Acid (targets seven factors contributing to uneven skin tone); and Intelligent peptide drone (encapsulated peptide for fast-onset skin brightening).
What results can I expect and by when?
ZO® Neck Complex Anti-Aging + Brightening Serum is backed by a 12-week independent, third-party clinical study of 46 subjects (females, ages 37-64, Fitzpatrick skin types I-VI). Individual results may vary based on skin condition, age, and consistency of use.