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Anti-Aging with ZO Skin Health essentials

Anti-Aging Skincare

ZO® anti-aging products are designed to address both the visible signs and key triggers of aging at every phase.
21 Results
Best Seller

Advanced barrier serum that defends against

environmental stressors + premature signs of aging

$190.00
Size
50 mL / 1.7 Fl. Oz.
4.5 (754)
New Beauty

Concentrated antioxidant serum that

defends against pollution + premature signs of aging

$195.00
4.0 (143)

Rejuvenating at-home peel that soothes + hydrates skin

$92.00
4.4 (221)

Luxuriously rich hydrator clinically proven to

rejuvenate the appearance of fragile skin and neck aging

$135.00
4.3 (271)

Vitamin C brightens skin + promotes a more even skin tone

$112.00
Size
50 mL / 1.7 Fl. Oz.
4.3 (675)

Glycolic and lactic acid complex designed to

exfoliate + brighten skin

$92.00
Size
50 mL / 1.7 Fl. Oz.
4.4 (198)

Lightweight serum that reduces surface oils

for an instantly matte finish

$68.00
4.0 (168)

Comprehensive program designed to promote

a smooth, even skin tone

$290.00
3.9 (54)

Formulated with 0.5% retinol to support the

visible improvement of wrinkles & skin texture

$175.00
Size
50 mL / 1.7 Fl. Oz.
4.4 (9)

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Frequently Asked Questions

How do I build an anti-aging skincare routine?

Start with Getting Skin Ready®: cleanse, exfoliate, tone. Then apply Prevent + Correct products AM and PM. Finish every morning with ZO® sunscreen. Your physician customizes the specific products and concentrations for your skin.

Should I use anti-aging cream in the morning or at night?

Most ZO® anti-aging formulas suit AM and PM use. Radical Night Retinol is specifically formulated for PM. Every morning system ends with a ZO sunscreen delivering Triple-Spectrum Protection®. Your physician determines your complete protocol.

What is the best skincare ingredient for anti-aging?

ZO® formulas combine retinoids, ZCORE®, ZPRO®, Vitamin C, Vitamin E, niacinamide, and alpha hydroxy acids, each targeting specific aging concerns. Your physician identifies the right combination for your skin.

Does anti-aging skincare work?

Yes, but formulation quality determines results. ZO® builds on clinically shown technologies including microencapsulated retinols, bioengineered plant stem cell complexes, and proprietary delivery systems, all developed by Zein Obagi MD over 35+ years.

When should I start using anti-aging creams?

There is no fixed starting age: it depends on your skin concerns and goals. Prevention can start in your mid-twenties. Consult a ZO provider to determine the right time and approach for you.

Why use anti-aging skincare products from ZO Skin Health?

ZO is physician-founded with nearly two decades of clinical innovation. Products are clinically shown and award-recognized by Cosmopolitan, Elle, and Harper's Bazaar, dispensed through a global network of authorized physicians.