Free Ground Shipping On Orders $99+*

Receive Up to 10% Off + Free Shipping On All Subscription Deliveries* Read More
Welcome to the ZO Skin Health Store for:
Find a Professional
National Eczema Association
Product video
4.7
(437)

Hydrating Crème

$125.00
Size
113 g / 4 Oz.

Hydrating Crème is a high-potency product. It is only available for purchase via our network of clinical professionals.

Find a Professional

Notify me when available

Please enter your email so we can alert you when the Hydrating Crème is back in stock. We promise not to spam you. You will be notified only once.

Soothing hydrator for dry, eczema-prone, and post-treatment skin. This lightweight skin protectant is clinically shown to soothe visible irritation, reduce the appearance of redness and itching, and replenish natural moisture to aid skin recovery.


Clinically tested | Free of Paraben, SLS, SLES, Phthalates, and Gluten

Dry to sensitized skin
Skin hydration
Post-procedure treatment
Barrier strengthening and resilience

Ophiopogon Japonicus Root Extract: Helps restore skin barrier function and hydration
Myristoyl Pentapeptide-11: Supports overall skin health
ZOX¹²®: Exclusive antioxidant complex of encapsulated vitamins A, C, and E delivers 12 hours of defense against free radical damage from environmental aggressors
Colloidal Oatmeal: Provides fast-acting skin soothing benefits

Seal of Acceptance by National Eczema Association
2025 Best Moisturizer, Pure Beauty Global Awards, Cosmetic Business Pure Beauty

For Better Results, Pair With:

CLINICALLY SHOWN RESULTS

Smoother, Calmer, Deeply Hydrated Skin

90%

saw a visible improvement in skin dryness by week 8

90%

saw a visible improvement in skin texture and smoothness by week

85%

reported that skin appeared less red by week 12

87%

reported a reduction in itching from dryness by week 8

- Before
- After
Hydrating Crème before-after-2 Before
Hydrating Crème before-after-2 After
Hydrating Crème before-after-3 Before
Hydrating Crème before-after-3 After
Science and Ingredients

Dry Skin Starts with a Broken Barrier

Healthy skin starts with a strong barrier that locks in hydration and keeps irritants out. When that barrier breaks down, skin loses moisture and turns dry, itchy, and red. Hydrating Crème works to repair the barrier and break the cycle.

Normalize Skin Barrier Resistance and Integrity

Works within the epidermis to restore barrier integrity and resistance while increasing hydration for instantly smoother, softer-feeling skin. Helps minimize the appearance of redness and itching associated with dryness while supporting cell renewal and natural skin recovery to reduce the intensity and frequency of flare-ups.

Replenish Skin's Natural Moisture to Aid in Skin Recovery

Clinically proven to reduce the signs of dry and sensitized skin.

Restore Skin Barrier Function

Exclusive 12-hour time-release antioxidant complex that protects the skin from free radicals and prevents premature aging.

EXPERT GUIDANCE

Apply as the last step in your AM + PM routine. Use SPF in the morning.

Apply to the face and neck.

ZO® Hydrating Crème is a supplementary hydrator applied as needed, after your Strengthen + Correct products. In the morning, follow with your ZO® SPF product. For intensive recovery during post-procedure phases, use as directed by your physician.

Replenishes skin’s natural moisture to aid in skin recovery.

Expert Guidance

Customer Reviews

Build Regimen

Build a Balanced Regimen

Your skin works as a system. Your regimen should too. Receive a fully personalized recommendation based on your skin health goals.

Build Your Regimen

Frequently Asked Questions

What makes ZO Hydrating Crème different from a regular moisturizer?

ZO® Hydrating Crème is a clinically developed functional hydrator, not a traditional moisturizer. Where conventional moisturizers work primarily from the surface down, ZO's functional hydrators are formulated to encourage the skin to hydrate from within by normalising barrier resistance and supporting the skin's own recovery processes. Hydrating Crème temporarily relieves symptoms of severely dry skin, calms visible irritation, and replenishes the skin's natural moisture to aid in recovery. It carries the National Eczema Association Seal of Acceptance, distinguishing it from standard over-the-counter moisturizers as a clinically validated option for reactive and compromised skin.

What are the key ingredients in ZO Hydrating Crème?

ZO® Hydrating Crème is formulated around four core actives. Ophiopogon Japonicus Root Extract helps restore skin barrier function and hydration. Myristoyl Pentapeptide-11 supports overall skin health. ZOX12®, ZO's exclusive antioxidant complex of encapsulated vitamins A, C, and E, delivers up to 12 hours of defense against free radical damage from environmental aggressors. Colloidal Oatmeal provides fast-acting soothing benefits for irritated, dry skin. The full ingredient list is available on the product page and product packaging.

Who is ZO Hydrating Crème formulated for?

ZO® Hydrating Crème is formulated for Normal to Dry and Dry to Sensitized skin. It is particularly suited to those with severely dry, rough, or flaking skin; skin sensitized by environmental damage, over-exfoliation, or chronic dryness; post-procedure skin requiring intensive hydration and calming support during recovery or those with eczema-prone conditions. Its National Eczema Association Seal of Acceptance provides third-party validation of its suitability for reactive and compromised skin.

When and how do I use ZO Hydrating Crème in my routine?

ZO® Hydrating Crème is a supplementary hydrator applied as needed, after your Prevent + Correct products. It can be used AM or PM. Apply a small amount to the face and neck. In the morning, follow with your ZO® SPF product. For intensive recovery during post-procedure phases, use AM and PM as directed by your physician.

Can ZO Hydrating Crème be used after a skin treatment or procedure?

Yes. ZO® Hydrating Crème is specifically indicated for post-procedure skin, providing barrier restoration support and intensive hydration when the skin is most compromised. Its key actives, including Ophiopogon Japonicus Root Extract and Colloidal Oatmeal, help soothe visible irritation and support the skin's natural recovery process. Always follow your physician's post-procedure care instructions for specific timing and product layering guidance.

Is ZO Hydrating Crème suitable for sensitive skin?

Yes. ZO® Hydrating Crème is formulated for Dry to Sensitized skin and is indicated for use on skin compromised by environmental damage, over-exfoliation, or chronic dryness. Its formulation restores hydration and soothes the appearance of visible redness, and with continued use skin feels healthier, smoother, and more hydrated. It carries the National Eczema Association Seal of Acceptance, providing independent validation of its suitability for reactive and sensitive skin. If you have specific skin conditions, consult your physician before use.