Welcome to the ZO Skin Health Store for:
Loading your bag

Growth Factor Eye Serum

$140.00
15 mL / 0.5 Fl. Oz.

Growth Factor Eye Serum is a high-potency product. It is only available for purchase via our network of clinical professionals.

Find a Professional

Notify me when available

Please enter your email so we can alert you when the Growth Factor Eye Serum is back in stock. We promise not to spam you. You will be notified only once.

Smoother, plumper, more awake-looking eyes. This growth factor eye serum targets the toughest signs of eye aging - fine lines, creasing, and hollowness, for skin that looks smoother, firmer, and visibly revived. Its cooling applicator soothes and refreshes tired eyes on contact.


Clinically tested | Free of Paraben, SLS, SLES, Phthalates, and Gluten

All skin types
Fine lines and wrinkles
Visibly smoothing and firming skin
Skin density and volume

ZO® Growth Factor Technology: Enzymatic + plantderived growth factors
Neuropeptide: Fast acting; improves the appearance of lines + wrinkles
Sodium acetylated hyaluronate: Advanced form of hyaluronic acid that plumps, replenishes hydration + supports a healthy skin barrier

For Better Results, Pair With:

EXPERT GUIDANCE

Apply AM + PM after cleansing, exfoliating, and toning.

Apply a pea-size amount to the orbital eye area. Using the cooling applicator tip, draw small, gentle circles into the eye orbital area until absorbed.

Apply after completing Getting Skin Ready® (cleanse, exfoliate, tone). Growth Factor Eye Serum is retinol-free and can be used alongside retinol products. In the morning, follow with your SPF.

Re-invigorates the look of tired eyes.

Avoid direct contact with the eye itself.

Expert Guidance

Customer Reviews

Build Regimen

Build a Balanced Regimen

Your skin works as a system. Your regimen should too. Receive a fully personalized recommendation based on your skin health goals.

Frequently Asked Questions

How do I use ZO Growth Factor Eye Serum?

Apply a pea-size amount to the orbital eye area morning and evening. Using the cooling applicator tip, draw small, gentle circles into the eye orbital area until absorbed. Apply after completing Getting Skin Ready® (cleanse, exfoliate, tone) and before any hydrator. In the morning, follow with your ZO® SPF. Avoid direct contact with the eye itself.

What results can I expect from ZO Growth Factor Eye Serum?

ZO® Growth Factor Eye Serum is formulated to help improve the appearance of expression lines, eye creasing, and hollowness while plumping the skin for a visibly revived look. The cooling applicator soothes the skin and re-invigorates the appearance of tired eyes. Results build with consistent AM and PM use. Individual outcomes vary based on skin condition, age, and consistency of use.

What makes ZO Growth Factor Eye Serum different from other growth factor eye products?

Most growth factor eye products rely on a single delivery mechanism. ZO® Growth Factor Eye Serum combines enzymatic and plant-derived growth factor technology with ZPRO®, a biomimetic sericin protein complex, alongside a targeted neuropeptide, sodium acetylated hyaluronate, and a dedicated eye complex formulated specifically for the physiologically distinct skin around the eye. The cooling applicator supports precise orbital application and helps soothe and re-invigorate the appearance of tired eyes. As a physician-dispensed formulation developed to clinical specifications, it is matched to your skin profile and concerns through your ZO® physician, rather than selected off-shelf.

Can ZO Growth Factor Eye Serum be used with retinol eye products?

Yes. ZO® Growth Factor Eye Serum is a retinol-free formulation, which means it can be used alongside retinol-based eye products without ingredient conflict. The two serve complementary functions: Growth Factor Eye Serum addresses the appearance of expression lines, creasing, and hollowness through enzymatic and plant-derived growth factor technology, while retinol eye products support cell turnover and natural collagen production. If using both, apply Growth Factor Eye Serum first and allow it to absorb before applying your retinol eye product. Your physician can advise on the optimal layering approach for your specific concerns.

Is ZO Growth Factor Eye Serum suitable for sensitive skin?

Yes. ZO® Growth Factor Eye Serum is indicated for all skin types. Its retinol-free formulation makes it accessible to those who cannot tolerate retinol around the delicate eye area, where skin is thinner, less sebaceous, and more reactive than the rest of the face. The formula combines enzymatic and plant-derived growth factors with ZPRO®, sodium acetylated hyaluronate for immediate hydration, and a dedicated eye complex including beta-glucan and antioxidant protection to support barrier integrity alongside active correction. The cooling applicator also minimises mechanical stress on the orbital area during application. If you have specific skin sensitivities or conditions, consult your physician before use.