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Firming Serum

$265.00
47 mL / 1.6 Fl Oz.

Firming Serum is a high-potency product. It is only available for purchase via our network of clinical professionals.

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Firmer, more lifted skin in 12 weeks. This anti-aging breakthrough visibly tightens and firms skin, softening the look of sagging and laxity for a more sculpted, defined contour. Lightweight and gentle enough for even sensitive areas.


Clinically tested | Free of Paraben, SLS, SLES, Phthalates, and Gluten

All skin types
Firming and tightening
Skin elasticity
Barrier strength and hydration

Sodium DNA: Supports the appearance of a more visibly defined facial contour
ZCORE™ complex: Helps improve the appearance of visibly sagging skin
ZO-RRS²®: Exclusive plant stem cell complex that provides powerful antioxidant benefits

For Better Results, Pair With:

CLINICALLY SHOWN RESULTS

Visibly Firmer Skin in 12 Weeks*

97%

of subjects saw significant improvement in firmness by week 12

93%

of subjects saw significant improvement in both mid-face and jawline skin sagging by week 12 as measured by expert clinical grader

88%

saw elasticity improvement by week 12

86%

of subjects said skin felt healthier by week 8.

83%

of subjects said skin appeared hydrated by week 8.

79%

of subjects saw a noticeable improvement in the overall appearance of their skin by week 8

baseline image firming serum Before
12 weeks after using firming serum After
baseline image firming serum Before
12 weeks after using firming serum After
baseline image firming serum Before
12 weeks after using firming serum After
Science and Ingredients

Firmness Starts Beneath the Surface

Over time, skin loses firmness, elasticity, and its ability to restore itself. ZO Firming Serum is specially formulated to visibly tighten and firm skin by supporting the structural integrity of skin and promoting cell renewal.

Strengthening a Foundation

Sodium DNA helps support fibroblast activity, the cells responsible for creating the structural support that keeps skin firm and elastic. It also promotes skin's natural renewal process, for a more visibly defined facial contour.

Strengthen to Prevent Sagging

ZCORE™ works underneath the surface of the skin to reinforce the natural structural support system. Over time, improving visible firmness, elasticity, and supporting a more lifted appearance of sagging skin.

Defend and Soothe

An exclusive plant stem cell complex provides the first line of defense by neutralizing free radicals, while calming visible redness.

EXPERT GUIDANCE

Use daily as part of your morning and evening routines.

Apply 1-2 pumps to face, neck, and décolletage. Massage gently upward using lifting motions.

Apply AM + PM after Getting Skin Ready® (Cleanse, Exfoliate, and Tone). In the morning, follow with SPF.

By week 8, skin feels healthier, appears hydrated and noticeably improved. By week 12 skin is visibly firmer and the appearance of sagging in mid-face and jawline is significantly improved.

Expert Guidance

Customer Reviews

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Frequently Asked Questions

What does ZO Firming Serum do?

ZO® Firming Serum is a clinically formulated serum indicated for visible skin sagging, loss of contour, and reduced elasticity. Its core technologies, Sodium DNA, ZCORE®, and ZO-RRS2®, work synergistically with skin's natural regeneration of collagen and elastin and provide antioxidants to help against daily oxidative stress. The result is visibly improved firmness and contour. Results are cumulative and build with consistent use.

What results can I expect before and after?

ZO® Firming Serum is backed by a 24-week independent third-party clinical study of 45 subjects (females, ages 40-69, Fitzpatrick skin types II-IV). At 8 weeks: 86% of subjects said skin felt healthier; 83% said skin appeared hydrated; 79% saw noticeable improvement in overall appearance. At 12 weeks: 97% of subjects showed significant improvement in firmness (Cutometer measurement); 93% showed significant improvement in the appearance of mid-face and jawline sagging (expert clinical grader); 88% elasticity improvement was measured. Individual results vary based on age, skin condition, and consistency of use.

How do I use ZO Firming Serum in my routine?

ZO® Firming Serum sits in the Correct step of your ZO® system. Apply after completing Getting Skin Ready® (cleanse, exfoliate, tone). AM: apply 1–2 pumps to face, neck, and décolletage; massage gently upward using lifting motions; follow with SPF. PM: apply as part of your active treatment step after toning. Use morning and evening for best results.

Is ZO Firming Serum suitable for sensitive skin?

Yes. ZO® Firming Serum is formulated for all skin types, including sensitive skin. It is a mild, lightweight formulation that achieves firming results through Sodium DNA, ZCORE®, and ZO-RRS2®, rather than through retinol or aggressive resurfacing agents. This makes it suitable for those who cannot tolerate high-potency retinol products or who are looking for a non-retinol approach to visible laxity and sagging.

How is ZO Firming Serum different from Growth Factor Serum?

Both are Step 3 Correct-layer serums but they address different skin concerns. ZO® Firming Serum targets visible skin laxity: it works on the structural firmness, particularly around the mid-face and jawline, via ZCORE® and Sodium DNA. Growth Factor Serum, powered by enzymatically plant-derived Human-Comparable Growth Factor Technology (IGF-1, EGF, acidic FGF, basic FGF, and VEGF), targets skin density, thinning, and the appearance of lines and wrinkles by supporting the skin's extracellular matrix. They are complementary: Firming Serum addresses structural shape and laxity; Growth Factor Serum addresses skin thickness and renewal. Many people incorporate both into their ZO® system, depending on their skin concerns and physician's guidance.